A new study from the University of Bath suggests that larger brain sizes in mammals are linked to stronger immune systems and increased lifespan. Analyzing genomic data from 46 mammal species, researchers found that those with longer lifespans exhibited expansions in immune-related gene families and relatively larger brains. The study identified 236 gene families positively correlated with maximum lifespan potential, enriched in genes associated with aging. Maximum lifespan potential indicates the longest age reached by individuals of a species, distinct from average lifespan affected by environmental factors. The researchers considered traits like brain size and age at maturity during their analysis, revealing a shared molecular mechanism associated with the evolution of lifespan and brain size. This correlation could shed light on factors influencing longevity across species and in humans, potentially guiding future therapeutic interventions in aging and related diseases. The findings indicate that both immune function and brain size significantly contribute to lifespan evolution.

Source đź”—