A new study from the University of Bath suggests that the size of a mammal's brain is associated with stronger immune systems and longer lifespans. Analyzing genomic data from 46 species, including cats, pandas, and dolphins, researchers found that larger brains and immune-related gene expansions correlate with increased lifespan potential. They identified 236 gene families linked to maximum lifespan potential, particularly enriched in immune system functions and previously associated with aging. This research highlights the shared genetic mechanisms between brain size and longevity, potentially offering insights into the aging process and avenues for therapeutic interventions in age-related diseases. Notably, the study emphasizes the importance of immune function and brain size in the evolution of long lifespans across species.

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